plasticity

Macro-connectomics and microstructure predict dynamic plasticity patterns in the non-human primate brain

The brain displays a remarkable ability to adapt following injury by altering its connections through neural plasticity. However, we know very little about why plasticity occurs in some areas of the brain, and not others. Here we investigated how the …

Plasticity in the Working Memory System: Life Span Changes and Response to Injury

Alterations in development of hippocampal and cortical memory mechanisms following very preterm birth

Deficits in memory function have been described in children and adolescents who were born very preterm (VPT), which can have profound effects on their school achievement and everyday life. However, to date, little is known about the development of …

Very Early Brain Damage Leads to Remodeling of the Working Memory System in Adulthood: A Combined fMRI/Tractography Study

Children who have brain injury following preterm birth often have working memory problems. When we assessed adults with the same injury, we found they no longer had severe working memory difficulties. By combining techniques to investigate the …

Neural compensation in adulthood following very preterm birth demonstrated during a visual paired associates learning task

Very preterm birth (VPT; textless 33 weeks of gestation) is associated with an increased risk of learning disability, which contributes to more VPT-born children repeating grades and underachieving in school. Learning problems associated with VPT …

Recovery from Post-stroke Aphasia: Lessons from Brain Imaging and Implications for Rehabilitation and Biological Treatments

Aphasia, a condition defined as the partial or complete loss of language function after brain damage, is one of the most devastating cognitive deficits produced by stroke lesions. Over the past decades, there have been great advances in the diagnosis …